chemical composition and general toxicity of essential oils extracted from the aerial parts of artemisia armeniaca lam. and a. incana (l.) druce growing in iran

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چکیده

the essential oils of the aerial parts of a. armeniaca and a. incana , collected from arasbaran area (east azarbaijan province, iran) were extracted by hydrodistillation and analyzed by gc-ms. in total, 16 and 40 constituents were identified and quantified in the oils of a. armeniaca and a. incana representing 80.5% and 84.6% of the oils, respectively. the essential oil of a. armeniaca was mainly composed of non-terpene hydrocarbons (24.8%). the major components of the oil were α–pinene (10.7%), nonadecane (10.0%), 6,10,14-trimethyl-2-pentadecanone (9.4%), spathulenol (7.8%) and z-verbenol (5.8%). the essential oil of a. incana was dominated by oxygenated monoterpenes (41.6%), with camphor (20.4%), 1,8-cineol (10.3%), z-verbenol (8.7%), β-thujone (8.3%) and α-thujone (5.6%), as major components . the essential oils were also subjected to general toxicity assay using brine shrimp lethality method. the toxicity profile of both oils indicated some degree of toxicity in comparison with podophyllotoxin.

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Chemical composition and general toxicity of essential oils extracted from the aerial parts of Artemisia armeniaca Lam. and A. incana (L.) Druce growing in Iran

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research in pharmaceutical sciences

جلد ۸، شماره ۱، صفحات ۶۵-۰

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